Solutions/Dietary Supplements

Dietary Supplement Regulatory Intelligence

Navigate DSHEA, cGMP, and labeling requirements with AI-powered compliance analysis. Ensure your supplements meet all regulatory standards.

Supported Regulations

DSHEA (Dietary Supplement Health and Education Act)

The foundational U.S. law defining dietary supplements and establishing the regulatory framework for their manufacture, labeling, and marketing.

Key Requirements Analyzed

  • -Dietary Ingredient Definition Compliance
  • -Structure/Function Claims Requirements
  • -Substantiation of Claims
  • -Disclaimer Requirements
  • -Adverse Event Reporting
  • -Notification Requirements

21 CFR 111 (cGMP)

Current Good Manufacturing Practice regulations for dietary supplements. Ensures products are manufactured consistently and meet quality standards.

Key Requirements Analyzed

  • -Personnel and Plant Operations
  • -Equipment and Utensils
  • -Production and Process Controls
  • -Holding and Distribution
  • -Laboratory Operations
  • -Records and Recordkeeping

NDI Notifications

New Dietary Ingredient notifications required for ingredients not marketed before October 15, 1994. Demonstrates reasonable expectation of safety.

Key Requirements Analyzed

  • -Identity of the NDI
  • -History of Use or Evidence of Safety
  • -Conditions of Use
  • -Manufacturing Information
  • -Toxicological Data

Labeling Requirements

Comprehensive labeling requirements for dietary supplements including Supplement Facts panel, ingredient lists, and required statements.

Key Requirements Analyzed

  • -Supplement Facts Panel
  • -Statement of Identity
  • -Net Quantity of Contents
  • -Ingredient Declaration
  • -Name and Place of Business
  • -Structure/Function Claims and Disclaimer

Advertising Compliance

FTC and FDA requirements for truthful and non-misleading advertising of dietary supplements.

Key Requirements Analyzed

  • -Truthful and Non-Misleading Claims
  • -Adequate Substantiation
  • -Clear and Conspicuous Disclosures
  • -Testimonial Requirements
  • -Competent and Reliable Scientific Evidence

International Standards

Regulatory requirements for dietary supplements in international markets including EU, Canada, and Australia.

Key Requirements Analyzed

  • -EU Food Supplement Directive
  • -Canadian NHP Regulations
  • -Australian TGA Requirements
  • -Codex Alimentarius Guidelines
  • -Import/Export Documentation

Platform Capabilities

Label Compliance Review

Comprehensive analysis of supplement labels against FDA requirements, including Supplement Facts panel, claims, and required statements.

cGMP Documentation Assessment

Evaluation of manufacturing documentation, SOPs, batch records, and quality systems against 21 CFR 111 requirements.

Claim Substantiation Analysis

Review of scientific evidence supporting structure/function claims to assess adequacy of substantiation.

NDI Notification Preparation

Analysis of safety data and documentation completeness for New Dietary Ingredient notifications.

Understanding Supplement Claims

Structure/Function Claims

"Calcium builds strong bones"

Must have substantiation, cannot claim to diagnose, treat, cure, or prevent disease

Nutrient Content Claims

"High in Vitamin C"

Must meet specific criteria defined in 21 CFR 101.54

Health Claims

"Adequate calcium may reduce the risk of osteoporosis"

Must be FDA authorized or qualified with disclaimer

Ready to Analyze Your Supplement Documentation?

Upload your labels, manufacturing documentation, and claims substantiation. Receive comprehensive compliance analysis to ensure market readiness.